Research 2019-10-23T10:54:59-05:00


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Title Description Author
Creatine powers fight against cancer, improves efficacy of immunotherapies Creatine is a popular organic acid that is widely used as a supplement by bodybuilders and athletes. A new study has found that creatine is a potent molecular battery that powers the immune cells to better fight cancer. Angela Betsaida B. Laguipo, BSN
Image Guided Cryoablation Image Guided Cryoablation of Cancer with Intra-Tumor Injection of anti-CTLA-4 and PD-1 Immune Checkpoint Inhibitors. Alternative Treatments for Cancer Jason R. Williams MD, Patrick E. Sewell MD, Mark A. Rosenberg MD
CpG Cryo Dendritic In vivo Colocalization of Antigen and CpG within Dendritic Cells Is Associated with the Efficacy of Cancer Immunotherapy. Stefan Nierkens, Martijn H. den Brok, Roger P.M. Sutmuller, Oliver M. Grauer, Erik Bennink, Mary E. Morgan, Carl G. Figdor, Theo J.M. Ruers, and Gosse J. Adema
DIPP4T Cell Trafficking Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. Rosa Barreira da Silva, Melissa E. Laird, Nader Yatim, Laurence Fiette, Molly A. Ingersoll & Matthew L. Albert
Local CTLA4 Injection Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8þ T-Cell–Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects Marieke F. Fransen, Tetje C. van der Sluis, Ferry Ossendorp, Ramon Arens, and Cornelis J.M. Melief
Off-Label Propanolol Off-Label Propanolol Reduces Melanoma Recurrence Vincenzo De Giorgi, MD; Marta Grazzini, MD; Silvia Benemei, MD; et al
Immuno-Thermal Ablations Immuno-thermal ablations – boosting the anticancer immune response Ryan Slovak, Johannes M. Ludwig, Scott N. Gettinger, Roy S. Herbst and Hyun S. Kim
Ablation Mechanisms Thermal ablation of tumors; biological mechanisms and advances in therapy. Katrina F. Chu and Damian E. Dupuy
Ablation Vaccine Saponin-based adjuvants create a highly effective anti-tumor vaccine when combined with in situ tumor destruction. Martijn H. den Brok, Stefan Nierkens, Jori A. Wagenaars, Theo J. Ruers, Carla C. Schrier, Eric O. Rijke, Gosse J. Adema
Intratumoral CTLA4 Intratumoral Anti-CTLA-4 Therapy: Enhancing Efficacy While Avoiding Toxicity. Martijn H. den Brok, Stefan Nierkens, Jori A. Wagenaars, Theo J. Ruers, Carla C. Schrier, Eric O. Rijke, Gosse J. Adema
Low Dose Cyclophosphimide Cyclophosphamide Unmasks an Antimetastatic Effect of Local Tumor Cryoablation. Moshe Yair Levy, Abhinav Sidana, Wasim H. Chowdhury, Steven B. Solomon, Charles G. Drake, Ronald Rodriguez, and Ephraim J. Fuchs
Intratumoral Immunization Intratumoral Immunization: A New Paradigm for Cancer Therapy Aurélien Marabelle, Holbrook Kohrt, Christophe Caux, et al.
Eradication Of Spontaneous Malignancy By Local Immunotherapy Human trials are set to commence after a potential cancer vaccine was shown to eliminate all traces of tumors in mice. Idit Sagiv-Barfi, Debra K. Czerwinski, Shoshana Levy, Israt S. Alam, Aaron T. Mayer, Sanjiv S. Gambhir and Ronald Levy